| Overview
of Influenza Hospitalization Surveillance
The California Emerging Infections Program (CEIP) conducts active,
laboratory-based surveillance for all laboratory confirmed influenza
cases hospitalized in our three-county catchment area. For every
case identified, we will complete a CDC generated case report
form. These data will be entered into a CDC generated database,
and transmitted to CDC on a monthly basis.
Project
Objectives
- Characterize the burden of and risk factors for laboratory-confirmed
influenza-associated
hospitalizations in a timely manner;
- Describe clinical and epidemiologic characteristics of hospitalized
case-patients;
- Conduct special studies (such as influenza vaccine effectiveness)
using the surveillance catchment area as a platform.
Main
Components of Influenza Hospitalization Surveillance Project
-Active laboratory based surveillance
-Special studies: Adult Influenza Vaccine Effectiveness Study
Case
Definition
-
A resident of the catchment area
- Admitted to a catchment area hospital between Oct 1 and April
30
- Admitted to hospital 3 days before or within 14 days after
a positive influenza test
- Evidence of a positive influenza test
- Case defining influenza tests include:
- A viral culture
- Immunofluorescence antibody staining (Direct [DFA] or indirect
[IFA])
- Reverse transcriptase polymerase chain reaction (RT-PCR)
- A commercially available rapid diagnostic test for influenza
Current Influenza Projects
The Adult Influenza Vaccine Effectiveness Study: Part of a multi
site study being conducted in collaboration with Centers for Disease
Control Influenza Division and nine other Emerging Infections
Programs nationwide. This study began October 1, 2008 and will
continue for three consecutive influenza seasons. Eligible cases
are adults 50 years and older, hospitalized with a laboratory-confirmed,
community-acquired influenza illness within 14 days of influenza
diagnosis. For each enrolled case, project personnel will recruit
two age and residence matched adults who have not been hospitalized
for influenza or for an acute respiratory condition during the
influenza season. Study personnel will enroll cases and controls
using a standardized telephone interview in either Spanish or
English. We will collect information for each participant about
influenza vaccine status and factors known to increase the risk
of serious complications from influenza infections.
Links
CDC Influenza
Information
California
Department of Public Health's California Influenza Surveillance
Project
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